Hi,
You can do that with a custom debug method definition. The easiest way to do it would be to select PyOCD in the debug settings, and then locate and copy the %LOCALAPPDATA%\VisualGDB\EmbeddedDebugPackages\com.sysprogs.arm.pyocd directory under a different name. You can then edit the EDP.XML file inside the new method directory to change the startup commands, stub location, or even define extra configuration properties.