I knew I’d have problems with this sooner or later. During the Mass Effect 2 installation from my backed-up isos the installer auto-ejects the virtual disc when it asks for disc 2. (I thought that’s ok, I’d have to eject it manually anyway) But when I mount disc 2 to the same letter it doesn’t seem to recognize it, keeps asking for disc 2. I think it’s because the device is disconnected when ejecting. I had to use virtualclonedrive to do the installation.
I think implementing an option to preserve the device when unmounting would solve this problem.